Andreas Moritz
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 Instead, statins artificially lower the level of cholesterol in the blood by blocking the enzyme in the liver that is responsible for making cholesterol. However, by creating an artificial "cholesterol famine" in the liver, bile is not formed properly, which increases the risk of gallstones and hinders the proper digestion of food. The side effects of statins are numerous; they include kidney failure, liver disease, and yes, heart disease (for more information on statins see Timeless Secrets of Health and Rejuvenation). |
Mehmet C. Oz., M.D. and Michael F. Roizen, M.D.
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 It's especially helpful for people who take statin drugs, because statins decrease levels of CQ10, which may be why statins can be associated with muscle cramps and pain— your arteries are literally being starved of energy and are crying for help.
Niacin (vitamin B3)
Sometimes
A dose of 500 milligrams can lower LDL cholesterol and lower triglycerides, and help raise HDL. Take it with aspirin when going to bed to help decrease the risk of hot flashes, a common side effect. You can take a higher dose but need to talk to your doc because higher doses often need to be prescribed (Niaspan). |
Andreas Moritz
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| The side effects of statins are numerous; they include kidney failure, liver disease, and yes, heart disease (for more information on statins see Timeless Secrets of Health and Rejuvenation). |
Connie Bennett, C.H.H.C. with Stephen T. Sinatra, M.D.
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 The newer cholesterol-lowering drugs (i.e., statins) not only lower cholesterol but also lower inflammatory mediators in the body.
And since we know that chronic relentless inflammation causes arteries to be on fire, controlling cholesterol by either lowering oxidized LDL or raising HDL will be advantageous. I still recommend statins as part of my plaque reversal plan in patients with documented coronary artery disease.
My grievance is when we aggressively treat high cholesterol numbers and not patients, and when we overprescribe these drugs for healthy people, especially women. |
Brenda Watson and Leonard Smith
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 High cholesterol runs rampant in the United States—feeding a billion-dollar industry that hawks statins, which are cholesterol-lowering drugs, as miracle drugs. An estimated 12 to 15 million American adults of every age and description depend on these drugs daily. They have become among the most popular prescription drugs in America.
Relying on statins, however, isn't a fail-safe solution. They can reinforce unhealthy habits (eating processed foods high in saturated fat, salt, and refined sugars) and serve as a disincentive to create a healthy lifestyle. |
Connie Bennett, C.H.H.C. with Stephen T. Sinatra, M.D.
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| I still recommend statins as part of my plaque reversal plan in patients with documented coronary artery disease.
My grievance is when we aggressively treat high cholesterol numbers and not patients, and when we overprescribe these drugs for healthy people, especially women. statins should be prescribed and chosen with great care and scrutiny. They may have many side effects, including changes in liver function; muscle pain or weakness; memory problems; depression; shortness of breath; and, on rare occasions, even death. |
Dr. Abram Hoffer, MD, FRCP (C) and Dr. Harold D. Foster, PhD
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 In contrast, the University of British Columbia Therapeutics Initiative sent a letter to 12,000 British Columbia doctors in 2003 doctors stating that statins "have not been shown to provide an overall health benefit" when prescribed to people who have not already had a stroke or heart attack and do not have cardiovascular disease.12 More recently, Dr Graveline has reported that statins cause transient global amnesia.13
Mitigating Tobacco Use
The use of tobacco is very stressful to the heart. |
Melody Petersen
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 Other companies were already selling five of these drugs known as statins, including Lipitor, Zocor, and Pravachol. But that did not stop the plans of the executives at the German chemical giant. They needed a new bestseller and were excited by the fast-rising use of statins by Americans, who were reminded every day to watch the levels of cholesterol in their blood. Thanks to the marketers of the first statin pills, "Know your numbers" had become a mantra of the fifty-and-older set.
There was something about Baycol, however, that made it stand out from the others. |
Ann M. Coulston and Carol J. Boushey
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 Antioxidant effects of statins.
Drugs Today (Bare) 40, 975-990.
111. Drinitsina, S. V., and Zateishchikova, D. A. (2005). Antioxidant properties of statins [Russian]. Kardiologia 45, 65-72.
112. Guzik, T. J., and Harrion, D. G. (2006). Vascular NADPH oxidases as drug targets for novel antioxidant strategies. 125. Drug Discovery Today 11, 524-533.
113. Richardson,M.A.,Sanders,T.,Palmer,J.L.,Greisinger,A.,and Singletary, S. E. (2000). Complementary/alternative medicine use in a comprehensive cancer center and the implications for oncology J. Clin. Oncol. 18,2505-2514. Burstein, H. J. |
Dr. Steven R. Gundry
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 One of the most ominous trends in modern medicine is the widespread prescribing of statins to lower cholesterol. statins work by limiting the action of an enzyme called HMG-CoA reductase in the liver, which is also responsible for the manufacture of C0Q10. In our rush to lower cholesterol levels, rather than looking at the cause for elevation, we have created a population with dangerously depleted levels of C0Q10 in muscle cells. |
Dr. Sharon Moalem
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 Today, the most widely prescribed therapy for high cholesterol is a class of drugs called statins. Although they are considered generally "safe" drugs, over time, statins can cause serious side effects, including liver damage. If you knew that you might be able to reduce your excess cholesterol by getting enough sunlight to convert it to vitamin D, wouldn't you rather hit the tanning salon before starting a lifetime of Lipitor? That's food for thought.
CHAPTER IV
HEY, BUD, CAN YOU DO ME A FAVA? |
Marshall Editions
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 Medication: statins, bile acid sequestrants, and intestinal cholesterol absorption inhibitors are the main medications prescribed. The specific medication used depends on the type of high cholesterol, which is measured as different lipoprotein types, that a patient is suffering from. If triglycerides are high, niacin and fish oil are used. Some of the side effects of cholesterol medication, especially from statins, are becoming well known. They include liver enzyme abnormalities due to liver damage and generalized muscle pain. These occur in some individuals but not all. |
Mehmet C. Oz., M.D. and Michael F. Roizen, M.D.
See book keywords and concepts |
| It's especially helpful for people who take statin drugs, because statins decrease levels of CQ10, which may be why statins can be associated with muscle cramps and pain— your arteries are literally being starved of energy and are crying for help.
Niacin (vitamin B3)
Sometimes
A dose of 500 milligrams can lower LDL cholesterol and lower triglycerides, and help raise HDL. Take it with aspirin when going to bed to help decrease the risk of hot flashes, a common side effect. You can take a higher dose but need to talk to your doc because higher doses often need to be prescribed (Niaspan). |
Byron J. Richards, CCN
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 Science supports the co-administration of Q10 with statins in all cases. statins provide their benefit by lowering cholesterol. In many cases the same could be accomplished by improving leptin and thyroid function and losing weight. Statin side effects work against the healthy response to exercise and may damage muscle function. Fixing leptin problems enhances muscle function and the health of muscle. Leptin management is clearly the first choice for prevention and long term resolution. statins, like all medications, will have an appropriate role in managing serious cardiovascular disease. |
Mark Sircus
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 Elderly people are more susceptible to fluoride toxicity.
62 statins and peripheral neuropathy; U. Jeppesen , D. Gaist, T. Smith S. H. Sindrup European Journal of Clinical Pharmacology Volume 54, Number 11 ;835 - 838 January 1999
63 The Peripheral Neuropathy Caused by statins Petition to Pharmaceutical Researchers and Manufacturers of America and companies listed was created by Druglntel Statin Users with Neuropathy and written by John Lehmann. |
Stephen T. Sinatra, M.D.
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 And, although the use of statins in high-risk coronary patients, especially those with inflammatory markers, is good medicine, overuse of these potent pharmacologic agents in otherwise healthy people is likely not justified, given the known and unknown side effects of their long-term use.
It is extremely important that physicians be aware of the potential for statins to adversely affect coenzyme Qio levels. This effect certainly has major implications for patients with cardiac disease, and is especially true for patients with congestive heart failure or an overactive thyroid gland. |
Steven V. Joyal
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 If you take a statin, we recommend that you supplement it with CoQIO. statins deplete CoQIO levels, and supplements help to minimize or avoid altogether many of the side effects associated with statins, including muscle pain and memory problems. In the vast majority of cases, CoQIO supplementation dramatically reduces statin-induced side effects.
A potentially very dangerous but rare side effect associated with high doses of potent statin drugs is muscle damage called rhabdomyolysis. If you take statin drugs and experience severe muscle pain or weakness, contact your physician immediately. |
| Unfortunately, the benefits (or lack of benefits) of statins for patients with type 2 diabetes are not clear from the results of these trials for various reasons, including study-design flaws, technical issues relating to statistics, and the small numbers of diabetic patients involved in some of the trials.
The best argument for the use of statins to reduce the risk of heart disease in diabetes can be seen in the results of the double-blind, placebo-controlled Collaborative Atorvastatin Diabetes Study (CARDS), in which more than 2,800 men and women participated. |
| Statins deplete CoQIO levels, and supplements help to minimize or avoid altogether many of the side effects associated with statins, including muscle pain and memory problems. In the vast majority of cases, CoQIO supplementation dramatically reduces statin-induced side effects.
A potentially very dangerous but rare side effect associated with high doses of potent statin drugs is muscle damage called rhabdomyolysis. If you take statin drugs and experience severe muscle pain or weakness, contact your physician immediately. |
Mark Sircus
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| Sponsor and perform research on how statins cause neuropathy. 3. Sponsor and perform clinical research on how to cure and reverse the neuropathy caused by statins. 4. Perform clinical research and recommend the best drug treatments to mitigate the pain and make other symptoms of statin-induced neuropathy more tolerable. 5. Proactively offer reparation to statin users who have suffered neuropathy. |
| Statins and risk of polyneuropathy
D Gaist, MD PhD, U Jeppesen, M Andersen, LAG Neurology 2002;58:1333-1337 ?2002 American Academy of Neurology statins and risk of polyneuropathy.
65 Participants receive injections of the toxin in six places in the calf muscle and then the leg is put into a cast. The idea is that this will help prevent pressure on the ball of the foot during walking. The ball if the foot is the area most affected by foot ulcers and allowing an ulcer to heal completely helps prevent recurrence, (www.diabetes-and-diabetics.com/about-diabetes/diabetic-complications-02. |
Andreas Moritz
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 A case-control study published in 2002 by the American Academy of Neurology found that long-term exposure to statins may substantially increase the risk of polyneuropathy, a neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously.
The problem with the new statin drugs is that they don't cause immediate side effects like the older cholesterol-lowering drugs did. The old cholesterol-reducing drugs prevented its absorption from the gut, which led to nausea, indigestion and constipation. |
Bottom Line Health
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| Many of the doctors on that panel had served as paid speakers, consultants or researchers for the large pharmaceutical companies that manufacture cholesterol-lowering drugs known as statins.
It's not surprising that high cholesterol has become an obsessive concern for everyone. We all know our "numbers," but high cholesterol isn't an illness. It's just one of many risk factors for a future illness—heart disease. |
Caldwell B. Esselstyn, Jr., M.D.
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 In 1987, when the first of the statins, lovastatin, became available, that became our drug of choice.2
The most frequent objection I had heard to my ideas about nutrition—and it's the same objection I hear to this very day—was that patients would never comply with such major changes in their diet. So I was determined to give them all the support I possibly could. Years before, I'd heard the pioneering physician J. Engelbert Dunphy quoted as saying that cancer patients are not afraid of suffering or dying, but are afraid of being abandoned. |
| In Chapter 5, I cited a study, recently reported in the New England Journal of Medicine, in which huge doses of statins successfully reduced patients' cholesterol levels well below 150 mg/dL. But even so, as their diet never changed, one out of four of the subjects experienced a new cardiovascular event or died within thirty months.
Unlike the drugs, plant-based nutrition has beneficial effects far beyond reducing cholesterol levels. It has a mighty impact on a host of other risk factors, as well: obesity, hypertension, triglyceride, and homocysteine levels. |
Marshall Editions
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| Some of the side effects of cholesterol medication, especially from statins, are becoming well known. They include liver enzyme abnormalities due to liver damage and generalized muscle pain. These occur in some individuals but not all.
TRADITIONAL CHINESE MEDICINE
514
Herbs: The herbs listed below are available from Chinese pharmacies and online.
• Shan Zha (hawthorn): Studies show that this fruit can help the body digest fat and reduce cholesterol. Hawthorn can be used alone, or as part of a formula. |
Andreas Moritz
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| As its reputation increased, it became a serious threat to the greatest drug money-maker of all time, the statins. To ensure the continuance of the big pharma business, red yeast rice was eliminated, thanks to the FDA.
Lemon rind and orange peel also contain a substance that lowers cholesterol quite dramatically. Even the researchers were shocked when they tested policosanol, a safe, natural substance found in citrus peels. In one study, 244 women with high cholesterol received either a placebo or policosanol. Researchers saw the bad cholesterol of the policosanol group plunge by 25 percent. |
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